Polynucleotides (Plinest)

The Science:

Polynucleotides (often referred to as PDRN) are highly purified DNA fragments originally derived from salmon DNA — a naturally bio-compatible material that works with your body to repair and regenerate skin tissue at a cellular level. They activate powerful skin-healing pathways, increase fibroblast activity, and boost collagen production while calming inflammation.

Polynucleotides work by deeply hydrating the skin, improving elasticity and firmness, and restoring structure where it’s been damaged by ageing, sun exposure, or stress. Unlike hyaluronic acid or topical skincare, they continue working beneath the surface long after treatment, promoting long-term rejuvenation and repair.

Why Everyone’s Calling It Magic:

Polynucleotides are having a “viral skincare moment” — and for good reason. They don’t just plump the skin… they help rebuild it. They improve texture, soften fine lines, lighten dark circles, reduce acne scarring and rejuvenate dull or crepey areas without adding volume. It’s a revolutionary treatment for clients looking for results that are natural, regenerative, and clinically proven.

Best for:

• Dark circles and under-eye hollows
• Loss of elasticity or crepey skin
• Skin ageing, fine lines, and dryness
• Acne scars and skin texture issues
• Pigmentation and sun damage
• Long-term skin strengthening and radiance